Availability:
50mg, 100 mg tablets
ACTIONS:
Inhibitions of Isoenzyme which results in vasodilatation and inhibition of platelet aggregation induced by colagen or arachidonic acid.
THERAPUTIC EFFECTS:
Increase skin temperature of the extremities and improves claudication. Effectiveness is indicated by increased ability to walk further without claudication.
USES:
Intermittent claudication.
CONTRAINDICATIONS:
Congestive heart disease. Concurrent therapy
with clopidogrel has not been studied for safety or efficacy. Pregnancy
and lactation.
CAUTIOUS USE:
Safety and efficacy in children <18y are not esteblished.
ROUTE AND DOSAGE:
Adult: PO 100mg b.i.d. 0.5 h before or 2 h after meals, may need to reduce to 50mg b.i.d. with contaminat ketoconazole, itraconazole, erythromycin, dilitiazem or omeprazole
PREGNANCY CATEGORY (US FDA):
Category C: Either studies in animals
have revealed adverse effects on the foetus (teratogenic or embryocidal
or other) and there are no controlled studies in women or studies in
women and animals are not available. Drugs should be given only if the
potential benefit justifies the potential risk to the foetus.
Cilostazol
5:44 PM
Ruzzie
