Scopolamine ref.: Davis's Drug Guide

Scopolamine (scoe-pol-a-meen) Scopace, Transderm-Scop, Transderm-V Classification Therapeutic: antiemetics Pharmacologic: anticholinergics Pregnancy Category C Indications Transdermal: Prevention of motion sickness. Management of nausea and vomiting associated with opioid analgesia or general anesthesia/recovery from anesthesia. IM, IV, Subcut: Preoperatively to produce amnesia and to decrease salivation and excessive respiratory secretions. PO: Symptomatic treatment of postencephalitis parkinsonism and paralysis agitans. Treatment of spasticity. Inhibits excessive motility and hypertonus of GI tract in irritable colon syndrome,...

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Meclizine Ref.: Davis's Drug Guide

Meclizine (mek-li-zeen) Antivert, Bonamine, Bonine, Dramamine Less Drowsy Formula Classification Therapeutic: antiemetics, antihistamines Pregnancy Category B Indications Management/prevention of: Motion sickness, Vertigo. Action Has central anticholinergic, CNS depressant, and antihistaminic properties. Decreases excitability of the middle ear labyrinth and depresses conduction in middle ear vestibular-cerebellar pathways. Therapeutic Effects: Decreased motion sickness. Decreased vertigo from vestibular pathology. Pharmacokinetics Absorption: Absorbed after oral administration. Distribution: Unknown. Metabolism and Excretion: Unknown. Half-life:...

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