Cyclobenzaprine
(sye-kloe-ben-za-preen)Amrix, Flexeril
Classification:
Therapeutic: skeletal muscle relaxants (centrally
acting)
Pregnancy Category B
Indications:
Management of acute painful musculoskeletal conditions associated with muscle spasm.
Unlabeled Use: Management of fibromyalgia.
Action:
Reduces tonic somatic muscle activity at the level of the brainstem. Structurally similar to tricyclic antidepressants. Therapeutic Effects: Reduction in muscle spasm and hyperactivity without loss of function.
Pharmacokinetics
Absorption: Well absorbed from the GI tract.
Distribution: Unknown.
Protein Binding: 93%.
Metabolism and Excretion:...
